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Semax Peptide Vial Lyophilisate For Lab Research
BATCH NR: NBLSX1007261101
TESTED FOR:
✓PURITY
✓WEIGHT
✓ENDOTOXINS(LPS)
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Date Tested: 01.07.2026
Purity: 99,883%
Weight: 9,83 mg
Endotoxin (LPS): Pass
Overview
Semax is a synthetic heptapeptide derived from a fragment of ACTH(4–10) with an added Pro-Gly-Pro sequence for stability. Originally developed at the Institute of Molecular Genetics, Russian Academy of Sciences, it has been studied for effects on cognitive function, neuroprotection, and neuroplasticity. Unlike ACTH, Semax does not exhibit significant hormonal activity in the literature; research has instead focused on neurotrophic factors, neurotransmitter systems, and cellular mechanisms of learning, memory, and neuronal adaptation.
Mechanism of Action (as reported in preclinical/clinical literature)
- Modulation of BDNF expression
- Influence on NGF signaling pathways
- Regulation of dopaminergic and serotonergic neurotransmission
- Support of synaptic plasticity and memory formation in models
- Modulation of inflammatory responses within neural tissue
- Enhanced neuronal resilience under experimental stress conditions
Proposed mechanisms are based on published experimental and clinical research; precise molecular pathways remain under investigation.
Research Applications
- Cognitive: learning/memory processes, attention/concentration mechanisms, information retention, cognitive performance models
- Neuroprotection: neuronal survival pathways, ischemia-related investigation, oxidative stress response, cellular resilience
- Neuroplasticity: synaptic adaptation, neural network remodeling, BDNF/NGF regulation, long-term potentiation research
- Neurotransmitter Research: dopamine signaling, serotonin regulation, neurochemical balance, brain communication mechanisms
- Brain Health: cognitive aging models, neural recovery investigation, CNS function, neuroinflammatory pathways
Technical Specifications
| Property | Value |
|---|---|
| Peptide Name | Semax |
| Alternative Name | ACTH(4–10) Pro-Gly-Pro |
| Molecular Weight | ~813.9 Da |
| Amino Acid Length | 7 amino acids |
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro |
| Molecular Formula | C37H51N9O10S |
| Appearance | Lyophilized powder |
| Purity | ≥99% (batch dependent) |
| Research Grade | For laboratory research use only |
Stability & Storage
Lyophilized: Store at -20°C; protect from light, heat, moisture; avoid repeated freeze-thaw. Reconstituted: Store at 2–8°C; sterile laboratory conditions; follow established research protocols.
Pharmacokinetic Notes (Research Data)
Plasma half-life generally reported as short (~10–20 min) in experimental models; biological effects may persist longer due to downstream regulation of neurotrophic/neurotransmitter systems.
Research Use Only — Please Read
FOR RESEARCH USE ONLY. This product is intended exclusively for laboratory research by qualified professionals.
This product:
- Is not approved for human use
- Is not approved for veterinary use
- Is not intended to diagnose, treat, cure, or prevent any disease
- Is not a dietary supplement
- Must not be used in clinical applications
The information provided is for educational and research purposes only and reflects findings from published scientific literature. Experimental results from in vitro, animal, or limited human research may not predict outcomes in broader populations.
Scientific References
1. Gusev EI, Skvortsova VI, Dambinova SA, et al.
Effects of Semax in patients with ischemic stroke.
Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova.
2. Ashmarin IP, Kamensky AA, Levitskaya NG, et al.
Synthetic ACTH analogue Semax displays nootropic-like activity in humans.
Neuroscience Research Communications. 1996.
3. Dolotov OV, et al.
Semax regulates BDNF-related signaling pathways in experimental models.
Bulletin of Experimental Biology and Medicine.