Peptide Storage Guidelines
Proper peptide storage relies heavily on whether the peptides are lyophilized (powder/freeze-dried) or in solution (reconstituted). Powdered peptides should be stored at -20°C or lower in a dry, dark place. Once reconstituted, they must be refrigerated at 2--8°C and used quickly to maintain integrity.
1. Lyophilized (Powder) Peptides (Freeze-dried peptides) are highly stable, but moisture and air exposure are their primary enemies.
- Temperature: Store at or below -20°C for long-term preservation. At this temperature, many peptides remain stable for several years.
- Moisture Control: Peptides easily absorb atmospheric moisture, causing them to degrade. Store vials in an airtight container with desiccant packs.
- Thawing Process: Before opening a cold vial, let it reach room temperature. This prevents atmospheric water from condensing on the peptide and causing degradation.
2. Reconstituted (Liquid) Peptides are significantly less stable in solution and are susceptible to degradation, oxidation, and bacterial growth.
- Temperature: Store strictly at 2--8°C (standard refrigerator temperature).
- Avoid Freezing: Do not freeze reconstituted peptides unless absolutely necessary, and only if divided into individual aliquots prior to freezing.
- Handling: Never subject reconstituted peptides to repeated freeze-thaw cycles. Thaw only what is needed immediately and discard unused portions.